Domaine d'activité
Recherche & Développement
Catégorie
Other
Localisation
Marcq-en-Barœul, France
Type de contrat
Permanent Contract
Experience
1 to 3 years

Description de l'offre

  • Developing automated ultra-HTP experimental assays (e.g. via FACS/flow cytometry and advanced microfluidics), protocols, workflows for ultra-HTP genetic engineering unit operations and processes, strain cultivation, HTP biological screenings in whole cell formats 
  • Writing scripts within existing commercial platform-specific software to drive operation of laboratory instruments and robotics applied to biological screenings 
  • Organizing and Supporting the validation and QC'ing of automated biological screening protocols 
  • Operating laboratory automation equipment during the execution of biological screenings 
  • Work with and train walk-in customer users on workflows and best practices 
  • Working with other automation engineers, assay development scientists, metabolic engineering scientists and data scientists to ensure the technical quality  
  • Identifying and leading improvements in group practices and protocols 

Qualifications

  • PhD in biology, cell biology, biochemistry, bioengineering, chemistry, chemical engineering or equivalent 
  • At least 2-year post-PhD or post-postdoc industry research experience in biotechnology, assay development, or high/ultra-high throughput screening with emphasis in FACS and flow cytometry 
  • Experience with automation platforms, especially automation of FACS screenings, is preferred; Experience with Beckman instrumentation, automation software and LIMS environment is highly desirable but not a must 
  • Demonstrated ability to develop novel cell-based screening assays 
  • Independently troubleshoot technically complex problems, and propose solutions or experimental plans to resolve or correct them 
  • Demonstrated ability to meet the demands of multiple concurrent projects 
  • Expertise in current technology and applications in microfluidics is desirable; hands on experience, development and micro-fabrication of microfluidic devices is a plus. 
  • Strong data and statistics background applied to HTP screenings; familiarity with LIMS environments (e.g. Benchling) and concepts as well as statistical software packages (MiniTab, SPSS, etc.); ability to script simple data analysis in one the following, Jupyter Notebooks, Matlab/Octave, Python or R is required 
  • Experience in project and/or resource management is a plus; additional familiarity with software tools such as Microsoft Project, Smartsheets, or other Lean Management tools is a plus 
  • Enzymology experience is desirable 
  • Familiarity with diverse organisms is a plus 
  • Ability to work in an international team, including good command of spoken and written English, cultural sensitivity, flexibility 

Description de l'entreprise

A key global player in fermentation for more than a century, Lesaffre, with a 2,2 billion euro turnover, and established on all continents, counts 10,700 employees and more than 85 nationalities. On the strength of this experience and diversity, we work with customers, partners and researchers to find ever more relevant answers to the needs of food, health, naturalness and respect for our environment. Thus, every day, we explore and reveal the infinite potential of microorganisms.

To nourish 10 billion people, in a healthy way, in 2050 by making the most of our planet’s resources is a major and unprecedented issue. We believe that fermentation is one of the most promising answers to this challenge.